# Internetwork traffic privacy for Amazon IoT SiteWise
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Connections between Amazon IoT SiteWise and on-premises applications, such as SiteWise Edge gateways, are secured over Transport Layer Security (TLS) connections. For more information, see [Data encryption in transit for Amazon IoT SiteWise](encryption-in-transit.md).

Amazon IoT SiteWise doesn't support connections between Amazon Regions, connections between Availability Zones within a Region, or connections between Amazon accounts.