FAQ - SAP NetWeaver on Amazon
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FAQ

Q. Can I use Amazon RDS for SQL Server as a database to deploy SAP NetWeaver based applications?

A. No, Amazon RDS for SQL Server is not certified by SAP for SAP NetWeaver based applications. However, it is certified to be used as database for SAP Business Objects BI (BObj BI)

Q. Can I use Microsoft Windows and Enterprise SQL Server AMI provided by Amazon (for example Microsoft Windows Server 2016 with SQL Server 2016 Enterprise)?

A. No, due to specific support requirement from SAP this is not a supported option. You will need to bring your own license (BYOL) for SQL Server. See SAP Note 2539944 - Windows Server / Microsoft SQL Server on AMI for details.